6/17/2023 0 Comments Etos diarreeremmer![]() It does not interfere with microtubular assembly. At low concentrations (0.3 to 10 µg/mL), cells are inhibited from entering prophase. At high concentrations (10 µg/mL or more), lysis of cells entering mitosis is observed. Two different dose-dependent responses are seen. Etomedac is cell cycle dependent and phase specific, affecting mainly the S and G2 phases. ![]() It inhibits DNA topoisomerase II, thereby ultimately inhibiting DNA synthesis. At low doses, it inhibits cells from entering cell cycle and at high doses, cells entering mitosis are lysed.Įtomedac is an antineoplastic agent and an epipodophyllotoxin (a semisynthetic derivative of the podophyllotoxins). Etomedac is a derivative of podophyllotoxin that inhibits DNA synthesis resulting in the arrest of the cell cycle.
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